In the study, researchers exposed human brain blood vessel cells to erythritol in amounts similar to what people might consume in everyday products. What they found was concerning.
The sweetener seemed to affect how the blood vessels in the brain work. Specifically, erythritol makes the cells produce less nitric oxide, a molecule that helps blood vessels relax and remain flexible.
It also increased the production of endothelin-1, which causes blood vessels to tighten. This combination could make blood vessels more prone to constriction, a condition that can increase the risk of serious issues like strokes.
The study also showed that erythritol could affect the body’s ability to dissolve blood clots naturally. The cells exposed to erythritol produced less t-PA, a natural compound that helps break down clots. Additionally, the erythritol exposure led to higher levels of free radicals, which are harmful molecules that can damage cells and tissues, potentially contributing to other health problems like heart disease.
While this research was conducted on cells in a lab, the results align with previous studies that suggest higher levels of erythritol in the bloodstream are linked to a higher risk of cardiovascular events, like heart attacks and strokes.
Because of these findings, the researchers are urging people to be more mindful of their erythritol intake. Many sugar-free and low-calorie products, which are often marketed as healthy alternatives, could contain higher amounts of this sweetener.
For those who regularly consume such products, it may be a good idea to check labels more carefully and consider limiting erythritol intake until more research can fully understand its long-term effects.
While erythritol has been popular as a sugar substitute, the new research highlights the importance of being cautious about its possible impact on health.
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