His family confirmed he passed away on Thursday, describing his final months as a courageous fight marked by advocacy and dedication to raising awareness of the disease.
Dane publicly revealed his ALS diagnosis in April 2025 and spent the months that followed using his platform to support patients and research.
Family statements highlighted his determination to make a difference, noting that he focused on fundraising and bringing public attention to ALS, the most common form of motor neurone disease. In recognition of his efforts, Dane was named “Advocate of the Year” by the ALS Network in late 2025.
Born with a versatile talent for television and film, Dane first gained widespread recognition for his portrayal of Dr. Mark Sloan, affectionately nicknamed “McSteamy”, on the long-running medical drama Grey’s Anatomy. Introduced in Season 2, he became a fan favorite, appearing in 139 episodes, and left a lasting mark on pop culture.
He later drew acclaim for his darker, complex role as Cal Jacobs on the hit teen series Euphoria, continuing through the show’s second season and filming scenes for its upcoming third season. Dane also starred as Captain Tom Chandler on the post-apocalyptic action series The Last Ship from 2014 to 2018.
His other work included recurring television roles in Charmed and Gideon’s Crossing, early appearances in The Wonder Years, Roseanne, and Saved by the Bell, as well as film roles in X-Men: The Last Stand, Marley & Me, Valentine’s Day, Burlesque, and Bad Boys: Ride or Die.
Tributes have poured in from co-stars and colleagues, who remembered Dane as a warm, humorous, and intelligent presence on set. Many praised his dedication to ALS advocacy, noting his final months were defined by generosity and purpose.
Dane is survived by his wife and two daughters, Billie and Georgia, whom his family described as the center of his world. His memoir, scheduled for release later this year, will offer a closer look at his life, career, and enduring efforts to make a difference for those affected by ALS.
Leave a Reply