{"id":2000106763,"date":"2026-03-28T17:21:00","date_gmt":"2026-03-28T15:21:00","guid":{"rendered":"https:\/\/new.igihe.com\/?p=2000106763"},"modified":"2026-03-29T12:42:04","modified_gmt":"2026-03-29T10:42:04","slug":"common-sugar-substitute-associated-with-brain-damage-and-increased-stroke-risk","status":"publish","type":"post","link":"https:\/\/new.igihe.com\/english\/common-sugar-substitute-associated-with-brain-damage-and-increased-stroke-risk\/","title":{"rendered":"Common sugar substitute associated with brain damage and increased stroke risk"},"content":{"rendered":"\n<p>In the study, researchers exposed human brain blood vessel cells to erythritol in amounts similar to what people might consume in everyday products. What they found was concerning. <\/p>\n\n\n\n<p>The sweetener seemed to affect how the blood vessels in the brain work. Specifically, erythritol makes the cells produce less nitric oxide, a molecule that helps blood vessels relax and remain flexible. <\/p>\n\n\n\n<p>It also increased the production of endothelin-1, which causes blood vessels to tighten. This combination could make blood vessels more prone to constriction, a condition that can increase the risk of serious issues like strokes.<\/p>\n\n\n\n<p>The study also showed that erythritol could affect the body\u2019s ability to dissolve blood clots naturally. The cells exposed to erythritol produced less t-PA, a natural compound that helps break down clots. Additionally, the erythritol exposure led to higher levels of free radicals, which are harmful molecules that can damage cells and tissues, potentially contributing to other health problems like heart disease.<\/p>\n\n\n\n<p>While this research was conducted on cells in a lab, the results align with previous studies that suggest higher levels of erythritol in the bloodstream are linked to a higher risk of cardiovascular events, like heart attacks and strokes.<\/p>\n\n\n\n<p>Because of these findings, the researchers are urging people to be more mindful of their erythritol intake. Many sugar-free and low-calorie products, which are often marketed as healthy alternatives, could contain higher amounts of this sweetener. <\/p>\n\n\n\n<p>For those who regularly consume such products, it may be a good idea to check labels more carefully and consider limiting erythritol intake until more research can fully understand its long-term effects.<\/p>\n\n\n\n<p>&nbsp;While erythritol has been popular as a sugar substitute, the new research highlights the importance of being cautious about its possible impact on health.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"1920\" height=\"1080\" src=\"https:\/\/new.igihe.com\/english\/wp-content\/uploads\/2026\/03\/man-headache-brain-stroke.jpg\" alt=\"\" class=\"wp-image-2000106764\"\/><figcaption class=\"wp-element-caption\">A common sugar substitute may quietly impair brain vessels and raise stroke risk.<\/figcaption><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>A recent study from the University of Colorado Boulder has raised alarms about erythritol, a sugar substitute that has become popular in many low-calorie and sugar-free products. Erythritol, commonly found in diet drinks, keto snacks, and protein bars, has long been thought to be a safe alternative to sugar, mainly because it has few calories and doesn\u2019t raise blood sugar levels. However, new research suggests it may carry some hidden risks.<\/p>\n","protected":false},"author":139,"featured_media":2000106764,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[75],"byline":[201],"hashtag":[],"class_list":["post-2000106763","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health","tag-homenews","byline-rania-umutoni"],"bylines":[{"id":201,"name":"Rania Umutoni","slug":"rania-umutoni","description":"","image":{"id":0,"url":"https:\/\/secure.gravatar.com\/avatar\/?s=96&d=mm&f=y&r=g","alt":"Default avatar","title":"Default avatar","caption":"","mime_type":"image\/jpeg","sizes":[]},"user_id":139}],"contributors":[{"id":201,"name":"Rania Umutoni","slug":"rania-umutoni","description":"","image":{"id":0,"url":"https:\/\/secure.gravatar.com\/avatar\/?s=96&d=mm&f=y&r=g","alt":"Default avatar","title":"Default avatar","caption":"","mime_type":"image\/jpeg","sizes":[]},"user_id":139}],"featured_image":{"id":2000106764,"url":"https:\/\/new.igihe.com\/english\/wp-content\/uploads\/2026\/03\/man-headache-brain-stroke.jpg","alt":"","caption":"","mime_type":"image\/jpeg","width":1920,"height":1080,"sizes":{"thumbnail":{"url":"https:\/\/new.igihe.com\/english\/wp-content\/uploads\/2026\/03\/man-headache-brain-stroke.jpg","width":150,"height":84},"medium":{"url":"https:\/\/new.igihe.com\/english\/wp-content\/uploads\/2026\/03\/man-headache-brain-stroke.jpg","width":300,"height":169},"medium_large":{"url":"https:\/\/new.igihe.com\/english\/wp-content\/uploads\/2026\/03\/man-headache-brain-stroke.jpg","width":768,"height":432},"large":{"url":"https:\/\/new.igihe.com\/english\/wp-content\/uploads\/2026\/03\/man-headache-brain-stroke.jpg","width":1024,"height":576},"full":{"url":"https:\/\/new.igihe.com\/english\/wp-content\/uploads\/2026\/03\/man-headache-brain-stroke.jpg","width":1920,"height":1080}}},"_links":{"self":[{"href":"https:\/\/new.igihe.com\/english\/wp-json\/wp\/v2\/posts\/2000106763","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/new.igihe.com\/english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/new.igihe.com\/english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/new.igihe.com\/english\/wp-json\/wp\/v2\/users\/139"}],"replies":[{"embeddable":true,"href":"https:\/\/new.igihe.com\/english\/wp-json\/wp\/v2\/comments?post=2000106763"}],"version-history":[{"count":3,"href":"https:\/\/new.igihe.com\/english\/wp-json\/wp\/v2\/posts\/2000106763\/revisions"}],"predecessor-version":[{"id":2000106820,"href":"https:\/\/new.igihe.com\/english\/wp-json\/wp\/v2\/posts\/2000106763\/revisions\/2000106820"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/new.igihe.com\/english\/wp-json\/wp\/v2\/media\/2000106764"}],"wp:attachment":[{"href":"https:\/\/new.igihe.com\/english\/wp-json\/wp\/v2\/media?parent=2000106763"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/new.igihe.com\/english\/wp-json\/wp\/v2\/categories?post=2000106763"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/new.igihe.com\/english\/wp-json\/wp\/v2\/tags?post=2000106763"},{"taxonomy":"byline","embeddable":true,"href":"https:\/\/new.igihe.com\/english\/wp-json\/wp\/v2\/byline?post=2000106763"},{"taxonomy":"hashtag","embeddable":true,"href":"https:\/\/new.igihe.com\/english\/wp-json\/wp\/v2\/hashtag?post=2000106763"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}