{"id":15501,"date":"2014-07-22T07:55:53","date_gmt":"2014-07-22T07:55:53","guid":{"rendered":"https:\/\/new.igihe.com\/exciting-drug-flushes-out-hiv\/"},"modified":"2014-07-22T07:55:41","modified_gmt":"2014-07-22T07:55:41","slug":"exciting-drug-flushes-out-hiv","status":"publish","type":"post","link":"https:\/\/new.igihe.com\/english\/exciting-drug-flushes-out-hiv\/","title":{"rendered":"‘Exciting’ Drug Flushes out HIV"},"content":{"rendered":"

{{Scientists say they have made an “exciting” step towards curing HIV by forcing the virus out of hiding.}}<\/p>\n

HIV can become part of someone’s DNA and lie dormant for decades, making a cure impossible.<\/p>\n

Early stage research in six people, reported at the Aids 2014 conference, shows that low-dose chemotherapy can awaken the virus.<\/p>\n

Experts said it was a promising start, but it was unlikely the drug would work on its own to cure HIV.<\/p>\n

Anti-viral drugs can drive HIV down to undetectable levels in the bloodstream, meaning people who are HIV-positive can have a near-normal life expectancy.<\/p>\n

But there is problem. HIV can incorporate its DNA into our own, where it lies beyond the reach of drugs and the immune system – it is known as the HIV reservoir.<\/p>\n

When drug treatment stops, the virus can leap out of the reservoir and renew its assault.<\/p>\n

International research is aimed at flushing the virus out of its reservoirs.<\/p>\n

A team at Aarhaus University in Demark tried using a chemotherapy drug, romidepsin, which is used in lymphoma.<\/p>\n

Six HIV patients with undetectable levels of the virus were enrolled into trial.<\/p>\n

They each received a reduced dose of romidepsin once a week for three weeks.<\/p>\n

There was a noticeable jump in viral levels in the blood in five of the patients.<\/p>\n

\"\"<\/figure>\n

agencies<\/p>\n","protected":false},"excerpt":{"rendered":"

{{Scientists say they have made an “exciting” step towards curing HIV by forcing the virus out of hiding.}} HIV can become part of someone’s DNA and lie dormant for decades, making a cure impossible. Early stage research in six people, reported at the Aids 2014 conference, shows that low-dose chemotherapy can awaken the virus. Experts […]<\/p>\n","protected":false},"author":3,"featured_media":2000053191,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[9],"tags":[101],"byline":[170],"hashtag":[],"class_list":["post-15501","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-science-technology","tag-internationl","byline-igihe"],"bylines":[{"id":170,"name":"IGIHE","slug":"igihe","description":"","image":{"id":0,"url":"https:\/\/secure.gravatar.com\/avatar\/?s=96&d=mm&f=y&r=g","alt":"Default avatar","title":"Default avatar","caption":"","mime_type":"image\/jpeg","sizes":[]},"user_id":8}],"contributors":[{"id":170,"name":"IGIHE","slug":"igihe","description":"","image":{"id":0,"url":"https:\/\/secure.gravatar.com\/avatar\/?s=96&d=mm&f=y&r=g","alt":"Default avatar","title":"Default avatar","caption":"","mime_type":"image\/jpeg","sizes":[]},"user_id":8}],"featured_image":{"id":2000053191,"url":"https:\/\/en-images.igihe.com\/IMG\/logo\/arton15501.jpg","alt":"","caption":"","mime_type":"image\/jpeg","width":0,"height":0,"sizes":{"thumbnail":{"url":"https:\/\/en-images.igihe.com\/IMG\/logo\/arton15501.jpg","width":1,"height":1},"medium":{"url":"https:\/\/en-images.igihe.com\/IMG\/logo\/arton15501.jpg","width":1,"height":1},"medium_large":{"url":"https:\/\/en-images.igihe.com\/IMG\/logo\/arton15501.jpg","width":1,"height":1},"large":{"url":"https:\/\/en-images.igihe.com\/IMG\/logo\/arton15501.jpg","width":1,"height":1},"full":{"url":"https:\/\/en-images.igihe.com\/IMG\/logo\/arton15501.jpg","width":0,"height":0}}},"_links":{"self":[{"href":"https:\/\/new.igihe.com\/english\/wp-json\/wp\/v2\/posts\/15501","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/new.igihe.com\/english\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/new.igihe.com\/english\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/new.igihe.com\/english\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/new.igihe.com\/english\/wp-json\/wp\/v2\/comments?post=15501"}],"version-history":[{"count":0,"href":"https:\/\/new.igihe.com\/english\/wp-json\/wp\/v2\/posts\/15501\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/new.igihe.com\/english\/wp-json\/wp\/v2\/media\/2000053191"}],"wp:attachment":[{"href":"https:\/\/new.igihe.com\/english\/wp-json\/wp\/v2\/media?parent=15501"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/new.igihe.com\/english\/wp-json\/wp\/v2\/categories?post=15501"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/new.igihe.com\/english\/wp-json\/wp\/v2\/tags?post=15501"},{"taxonomy":"byline","embeddable":true,"href":"https:\/\/new.igihe.com\/english\/wp-json\/wp\/v2\/byline?post=15501"},{"taxonomy":"hashtag","embeddable":true,"href":"https:\/\/new.igihe.com\/english\/wp-json\/wp\/v2\/hashtag?post=15501"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}