Category: Health

  • Insulin Breakthrough Could See End to Needles

    Breakthrough Australian research mapping how insulin works at a molecular level could open the door to novel new diabetes treatments, ending daily needle jabs for millions, scientists said Thursday.

    A Melbourne team have been able to lay out for the first time how the insulin hormone binds to the surface of cells, triggering the passage of glucose from the bloodstream to be stored as energy.

    Lead researcher Mike Lawrence said the discovery, more than 20 years in the making, would make new and more effective kinds of diabetes medication possible.

    “Until now we have not been able to see how these molecules interact with cells,” said Lawrence, from the Walter and Eliza Hall Institute of Medical Research.

    “We can now exploit this knowledge to design new insulin medications with improved properties, which is very exciting.”

    Lawrence said the team’s study, published in the latest edition of Nature, had revealed a “molecular handshake” between the insulin and its receptor on the surface of cells.

    “Both insulin and its receptor undergo rearrangement as they interact — a piece of insulin folds out and key pieces within the receptor move to engage the insulin hormone,” he said of the “unusual” binding method.

    Understanding how insulin attaches to cells was key to developing “novel” treatments of diabetes, a chronic condition in which the pancreas does not produce enough insulin or the body cannot use it properly.

    “The generation of new types of insulin have been limited by our inability to see how insulin docks into its receptor in the body,” said Lawrence.

    “This discovery could conceivably lead to new types of insulin that could be given in ways other than injection, or an insulin that has improved properties or longer activity so that it doesn’t need to be taken as often.”

    Importantly, he said it could also have ramifications for the treatment of diabetes in developing nations, allowing for the creation of more stable insulins that do not need refrigeration.

    There are an estimated 347 million diabetes sufferers worldwide and diagnoses are increasing, particularly in developing countries, due to growing levels of obesity and physical inactivity.

    It is expected to be the seventh leading cause of death in the world by 2030, with the World Health Organisation projecting total deaths from diabetes will rise by more than 50% in the next 10 years.

    Complications of diabetes include blindness, limb amputation and kidney failure.

    AFP

  • Clarifications on Drug Stocks in Rwanda Hospitals

    Following some recent media reports alleging drug stock-outs in a few health facilities especially within Kigali City, the Ministry of Health would like to inform the general public that there’s no shortage of drugs in the country.

    Particularly, the Ministry of Health would like to make the following key clarifications:

    Since June 2012 the Ministry of Health has been monitoring on a weekly basis the stock levels of vital medicines and supplies in the 43 District Hospitals and 30 District Pharmacies across the country after an old procurement process had been stopped for health and safety reasons.

    This constant monitoring system has allowed reduction of drug stock-outs from 23% at the District Hospitals to 2% today and from 13% at the District Pharmacies to 4.9% as of 4th January 2013.

    In December 2012, this monitoring system was extended to National Referral Hospitals and the recent reports show a decreasing trend of stock-out in those hospitals from an average of 12% in December 2012 to 7 percent as of 4th January 2013.

    We are committed to reducing these figures even further to ensure availability of all key drugs within our health facilities.

    The problem of drug stock-out reported in Kibagabaga hospital during the festive season was a result of delays in payment of an outstanding bill that this hospital owed to the Gasabo district pharmacy.

    This too, was linked to the delay in footing the hospital bill by the district mutuelle pooling system. However, when the Ministry of Health in collaboration with Gasabo District intervened immediately, the problem was instantly solved as communicated through Media last Friday.

    The information issued by The New Times on the 08th January 2013 is an exaggeration of the situation and should not be considered as a general picture of availability of drugs and other health commodities in the country.

    There’s no shortage of essential drugs and only problem we identified in Kibagabaga district was a result of poor coordination between different entities at local level, which we immediately addressed.

    The Ministry of Health in partnership with the Ministry of Local Government are committed to be more vigilante in coordinating the and improving the management of stocks of medicines and other health commodities at district level to respond adequately to the expectation of our patients.

    Done in Kigali on the Jan 8th, 2013

    Dr. Agnes BINAGWAHO
    Minister of Health

  • Zim Artist Dismisses HIV Rumours

    Zimbabwe’s music icon Oliver Mtukudzi has dismissed rumours suggesting that he is HIV positive.

    Speaking in an interview aired by CNN on its African Voices programme, Tuku dismissed the reports as mere speculation.

    “I am not HIV positive myself, but I have dealt with a lot of programmes on HIV and Aids.

    “I have had a close encounter with Aids when I lost four of my band members, including a brother, to the pandemic in a space of two months.”

    Tuku, as Mtukudzi is affectionately known in music circles, made the revelations in reaction to growing speculation that he was HIV positive on account of his gaunt frame.

    “My brother Robert died of Aids, so I had all the reason to try and help and give awareness to the people and fight the stigma.

    “I am glad the stigma in Zimbabwe has fallen away, though not completely.

    “Stigma is just an attitude. And the fact that people now talk about HIV and Aids freely shows that it has fallen away. People no longer hide it.”

    Tuku said he was diabetic; hence his often sickly look, adding that rumour-mongers were basing their speculation on that condition.

    The 60-year-old music guru said he was the first Zimbabwean musician to be approached by the World Health Organisation in the 1980s to start Aids awareness programmes through song and dance.

    “I am one of the very first artistes in Zimbabwe to be approached about HIV by WHO in the year 1987.

    “Nobody knew about the disease in Zimbabwe, and I was lucky to get the material about the disease.

    “I had to learn and come up with a song, which saw me going to Switzerland where I actually saw people infected and affected, so I had a better understanding of the disease than my fellow artistes because they had not seen it and I had seen that,” he told Nkepile Mabuse of CNN’s African Voices.

    These experiences, Tuku said, had pushed him to embrace HIV as a key theme in his decades-long musical career hoping to fight stigma and raise awareness through his powerful lyrics.

    Tuku’s songs that address HIV and Aids-related issues include “Tapera”, “Todii” and “Stay with one Woman” among others.

    Last year, Mtukudzi won critical acclaim when he was appointed Unicef Goodwill Ambassador to raise Aids awareness in eastern and southern Africa.

    Unicef regional director Elhadj As Sy said Tuku had demonstrated a genuine commitment to communicating strong and clear messages about the importance of child and young people’s rights, including their right to live free from HIV and Aids on the occasion of the latter’s Unicef ambassadorial appointment.

    Herald

  • Blood Shortage Hits South Africa

    South Africa is facing a shortage of blood stocks as the national level dips to only a two-day supply, according to a media report on Saturday.

    Due to the low supply, blood will only be given in “absolute core emergencies” such as accidents, SA National Blood Service spokesperson Vanessa Raju told local press.

    Some planned surgeries and treatments requiring blood will be put off until stocks are restored.

    “It is not a good situation to be in but we have to make do…until the situation changes,” she said.

    Raju said national blood stocks should be at a five day supply but donations have fallen off due to the holiday.

    “People are on holiday and now some will be busy with getting their children ready for the new school year, so blood donation is not high on the list of things to do, resulting in low levels,” Raju told the paper.

    SAPA

  • Drugs Dispatched to Kibagabaga Hospital

    Yesterday IGIHE published two stories about the problem of insufficient drugs at Kibagabaga hospital and a patient Ntirenganya who had stayed at the hospital facility without recieiving any medication yet he had been involved in an accident.

    Ntirenganya needed an urgent operation but he had to stay for over 12 days because he lacked Health insurance cover. The Doctors only bandaged his left leg.

    However, the stories went viral and caused concerned authorities to immediately intervene.

    Ntirenganya later in the afternoon was granted an immediate operation.

    Another report indicates cartons of drugs have been dispatched to Kibagabaga hospital and other health centers lacking drugs.

    The Ministry of Health has allocated drugs to the Hospital.

    The Permanent Secretary of the Ministry of Health Dr. Uzziel Ndagijimana told Journalists that since 3rd January, 2013 more drugs are being sent to Hospitals that were lacking drugs.

    Dr Uzziel pledged to follow up on drug shortages as soon as possible.

    He explained that the problem was due to failure of collaboration between Kibagabaga Hospital and Gasabo District which was not allocating some money to Hospital.

    Ndagijimana also said the number of patients going to Kibagabaga Hospital was increasingly going up since the beginning of 2012 and some District were not paying Health insurance fees which facilitate the treatment of the patients.

  • Mukama Sector Residents Want Gov’t Help

    Residents of Gishoro in Mukama sector located in Nyagatare have resorted to use of traditional stretchers to carry the sick to hospital.

    The residents sight the poor status of roads in the area which cars could not navigate.

    However,Hakuzweyezu Emmanuel a local leader in the area says there are efforts to find solutions to the prevailing poor roads in the area.

    The only nearby health center is at Cyondo in Kiyombe sector.

    Gashora residents say there is no development in their area noting that they single handedly established the only road linking them to Kiyombe Sector, however, there is need for building a bridge to cross over the river linking the two sectors.

  • Kibagabaga Hospital Lacking Drugs

    Kibagabaga Hospital Lacking Drugs

    Patients at Kibagabaga hospital in Gasabo District are complaining of drug shortages.

    Hospital officials have said the shortage is due to the fact that Gasabo District has not paid about Rwf 300 Millions that the District owes the hospital inform of contributions to Health Insurance Scheme.

    A district official in charge of Social Affairs in Gasabo District noted that the problem of lack of drugs at the hospital is related to regulations established by the Ministry of finance regarding the financing of Health insurance scheme.

    However, the Permanent Secretary in the Ministry of Health, Dr. Uzziel Ndagijimana, slammed such explanations pledging immediate follow-up to solve problems of drug shortages in that hospital.

    Meanwhile Ntirenganya(see photo), a patient at Kibagabaga hospital has not been attended to for the past 12 days since he got involved in a car accident.

    Ntirenganya is said to have no Health Insurance cover which has resulted into his situation of not being accorded any treatment.

    He said, He is poor and is unable to get Frw3000 required to obtain Health Insurence.

    Ntirenganya was knocked by a car in Muhanga district on December 21, 2012. since then he has been at Kibagabaga hospital without recieving anyform of treatment.

    Doctors have only bandaged Ntirenganya’s left leg.

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  • How Maize Syrup Might Be Making Us Hungry & Fat

    Grocery store aisles are awash in foods and beverages that contain high-fructose corn syrup. It is common in sodas and crops up in everything from ketchup to snack bars.

    This cheap sweetener has been an increasingly popular additive in recent decades and has often been fingered as a driver of the obesity epidemic.

    These fears may be well founded. Fructose, a new study finds, has a marked affect on the brain region that regulates appetite, suggesting that corn syrup and other forms of fructose might encourage over-eating to a greater degree than glucose.

    Table sugar has both fructose and glucose, but high-fructose corn syrup, as the name suggests, contains a higher proportion of fructose.

    To test how fructose affects the brain, researchers studied 20 healthy adult volunteers. While the test subjects consumed sweetened beverages, the researchers used fMRIs (functional magnetic resonance imaging) to measure the response of the hypothalamus, which helps regulate many hunger-related signals, as well as reward and motivation processing.

    Volunteers received a 300-milliliter cherry-flavored drink sweetened with 75 grams (equivalent to about 300 calories) of fructose as well as the same drink sweetened with the same amount of glucose.

    These different drinks were given, in random order, at sessions one to eight months apart. The researchers also took blood samples at various time points and asked volunteers to rate their feelings of hunger and fullness.

    Subjects showed substantial differences in their hypothalamic activity after consuming the fructose-sweetened beverage versus the one sweetened by glucose within 15 minutes. Glucose lowered the activity of the hypothalamus but fructose actually prompted a small spike to this area.

    As might be expected from these results, the glucose drink alone increased the feelings of fullness reported by volunteers, which indicates that they would be less likely to consume more calories after having something sweetened with glucose than something sweetened with more fructose.

    Fructose and glucose look similar molecularly, but fructose is metabolized differently by the body and prompts the body to secrete less insulin than does glucose (insulin plays a role in telling the body to feel full and in dulling the reward the body gets from food).

    Fructose also fails to reduce the amount of circulating ghrelin (a hunger-signaling hormone) as much as glucose does.

    (Animal studies have shown that fructose can, indeed, cross the blood-brain barrier and be metabolized in the hypothalamus.) Previous studies have shown that this effect was pronounced in animal models.

    The study, led by Kathleen Page, of Yale University School of Medicine and published online January 1 in JAMA, The Journal of the American Medical Association, was small and was not able to pinpoint precise neural circuits that might be affected by the sweeteners.

    But the results, along with other research, suggest that, thanks to the “advances in food processing and economic forces” that have boosted the intake of fructose, added sugar and high-fructose corn syrup are “indeed extending the supersizing concept to the population’s collective waistlines,” wrote Jonathan Purnell, of the Division of Endocrinology, Diabetes, and Clinical Nutrition, and Damien Fair, of the Department of Behavioral Neuroscience, both of Oregon Health & Sciences University in Portland, who coauthored an essay that appeared in the same issue of JAMA.

    Could fructose consumption alone really be playing such an outsized role in expanding our pant sizes? “A common counterargument is that it is the excess calories that are important, not the food. Simply put: just eat less,” Purnell and Fair noted.

    “The reality, however, is that hunger and fullness are major determinants of how much humans eat, just as thirst determines how much humans drink.

    These sensations cannot simply be willed away or ignored.” In order to eat less (and consume fewer calories overall), they argued, then, one should avoid foods or ingredients that fail to satisfy hunger.

    And that, according to the results from the new study, would mean those fructose-sweetened foods–and drinks.

  • Maternal Mortality Slightly Dropped in Rwanda

    The year 2012 left Rwanda’s maternal mortality dropped from 750 of every 100,000 in 2005 to 134 in 2012.

    Statistics also show that deaths of children under the age of five have fallen from 152 of every 1000 in 2005 to 54, while the number of deaths caused by malaria reduced greatly, from 54% in 2005 to 6%.

    In the health sector, diseases like malaria that had afflicted Rwandans for a long time, as well as child and maternal mortality continue to reduce significantly.

    Rwanda faces a generalized epidemic, with an HIV prevalence rate of 3 percent among adults ages 15 to 49.

    The prevalence rate has remained relatively stable, with an overall decline since the late 1990s, partly due to improved HIV surveillance methodology.

    In general, HIV prevalence is higher in urban areas than in rural areas, and women are at higher risk of HIV infection than men.

    Rwanda’s President Paul Kagame has said Rwanda will continue to put more effort in health sector as well as ensuring that all Rwandans are accessing medical care.

    “We will continue to fight malnutrition and give our doctors advanced training to fight HIV/AIDS” Kagame assured

  • Britain’s Thatcher leaves hospital: Reports

    Britain’s former prime minister Margaret Thatcher has left hospital after successful bladder surgery, British media have reported.

    The 87-year-old was discharged on Saturday. sources close to the former premier said, but her spokeswoman did not immediately return calls on Sunday seeking confirmation.

    The former premier, who led Britain from 1979 to 1990, was admitted to hospital on December 20 for a minor operation to remove a growth from her bladder.

    The former Conservative Party leader remains the only female premier in British history.

    Media said Thatcher was “convalescing privately” after 10 days of treatment at an undisclosed hospital. Her west London home appeared to be empty at the weekend,